Showing 8 results for Heidarian
Zahra Ahmadipour, Mehdi Heidarian , Ebrahim Roumina, Javad Etaat,
Volume 4, Issue 3 (Summer 2022 2022)
Abstract
Division of territorial and demographic area of country into electoral districts is the first step to facilitate elections and provide a suitable background for a fair proportion between the number of lawmakers and the population of the country. Drawing electoral districts must be in such a way that guarantees the justice and equality among citizens and leads to the formation of democratic parliament that represents different groups of the people. The present study has assessed trend of approval of the bill to reform the table of electoral districts of the Islamic Consultative Assembly and the number of lawmakers in 2000. This research is applied in terms of purpose and is descriptive in terms of nature and general method. The findings show that demographic indicators, adaption to administrative divisions, extent, place competition, deprivation, locating in border areas, and finally economical and industrial situation were the most important effective indicators in increasing lawmakers and reforming electoral districts in 20 cases. Lack of definition of indicators for criteria of Article 64 of the Constitution (human, political, geographical and alike) and failure to calculate their weight and share in redistricting due to the lack of a redistricting part in ministry of interior have led to spatial injustice in increasing the number of lawmakers, separating and annexation some electoral districts in government bill.
Volume 6, Issue 20 (6-2018)
Abstract
Khaqani is a poet of Arrani style (Azerbaijani), and one of the most prominent features of this style is the use of various tools to make the discourse difficult. Having benefited from a reach cultural background besides a deep understanding of science and technology of his own era, Khaqani has created the magnificent images and has avoided any obscenity in his words. In other words, this diversity and variety in his poetic images may be due to the extent of Khaqani's information, research and his knowledge of historical interpretive books. One of the tools used by this poet to create his own images is allusion which can be considered a featured style of Khaqani due to its high frequency in his Divan. In his allusions, Khaqani occasionally refers to the indications which we cannot find their resources and references in the official and written literature; therefore we should search folk and oral narratives to find those references. In this research, we intend to look at the sources of some Shahnameh allusions of Khaqani which are based on oral and folk narratives and they are not mentioned in the official and written sources.
Volume 15, Issue 2 (5-2024)
Abstract
APC gene in ctDNA has been proposed as a potential biomarker for cancer diagnosis. A biosensor based on a multi-walled carbon nanotube (MWCNT) and DNA probe with fluorophore FAM (6-carboxyfluorescein) for detection of APC gene in ctDNA was developed to identify patients with colorectal cancer (CRC).
This method was designed based on the adsorption and immobilization of FAM-labeled single-stranded DNA (ssDNA) on MWCNT, which leads to the quenching of FAM fluorescence emission. By adding its cDNA could release single-stranded DNA probe (ssDNA) from the MWCNT surface and a double-stranded DNA (dsDNA) was formed. It led to the return of FAM fluorescence emission. While in the case of non-complementary DNA the corresponding dsDNA was not formed and therefore we did not have the return of FAM fluorescence emission. The results of this study showed that the biosensor based on carbon nanotubes can be used as a high-sensitivity method for the early detection of CRC.
Volume 16, Issue 1 (3-2016)
Abstract
Shaped charges are explosive devices with a high penetration capability and are used for both civilian and military purposes. In civilian applications shaped charge devices are used in demolition works, oil drilling and mining. In the military applications, shaped charges are used against different kinds of armors and Protective Structures. Analysis of forming and penetration of shaped charge projectiles issue is so complex that include explosion of charge, propagation of the shock wave in the charge, hitting the shock wave to the liner, liner deformation, projectile formation and finally striking projectile to target until it stops. According to the complexity of Behavior of the concrete during the Penetration of the Jet, the material models shoude be able to model the effect to large deformation, high hydrostatic pressure, high strain rate and failure. Although there are many references about Numerical simulation of shaped charge Jet in the armor targets, however it was not found any comprehensive sources about penetration of shaped charge in the reinforced concrete targets. Experimental results suggest that both kinetic energetic projectile and shaped charge are capable of destroying concrete targets, but the magnitudes of damage due to them are different. Compared with a kinetic energy projectile, a shaped charge has more significant effect of penetration into the target, and causes very large spalling area. In this paper, AUTODYN software was used to numerical simulation of shaped charge jet formation and target penetration. Different solver and modeling alternatives of AUTODYN were evaluated for jet formation and penetration problems. Euler solver of the AUTODYN was used to jet formation simulations and Lagrange solver was used for penetration simulations and both models were 2D axisymmetric. To simulate the penetration performance of the RPG – 7 charge, both the jet and the target were modeled by Lagrangian elements. The results of jet formation simulations, performed by the Euler solver were used to determine the properties of the jet. Penetration simulations were performed for a fixed 2 CD standoff distance. The jet material distribution obtained by the Euler solution at 2 CD standoff distance was mapped onto the Lagrange solver. The quality of this Euler-to-Lagrange mapping was limited to the mesh resolution of the Lagrangian jet part. The first goal of this research is presentation of a reliable method to numerical simulation of Penetration of shaped charge of RPG – 7 into the concrete targets by use of available software tools. Therefore, simulation results were compared to the experimental results in three stages that Include the jet formation, jet Penetration in armor targets and behavior of concrete target against Penetration. The second goal is determination of the safe thickness of conventional concrete targets against the Penetration of RPG – 7 weapen and investigation of the behavior of this concrete type of target in terms of penetration depth, hole diameter and failure of the front and rear surfaces of the target.
Volume 22, Issue 1 (Winter 2018)
Abstract
Aims: The correlation between high levels of blood lipid with the induction of some diseases indicates significant effects of hyperlipidemia and especially on the immune system, inflammatory response, and secretion of cytokines. This is due to changes in the composition of cholesterol in the cell membrane and macrophage cytoplasm, which disrupts the signaling pathway necessary for the innate immune response. The purpose of this study was to investigate the effect of on phenotype properties of T cells and the expression of its associated activation markers.
Materials & Methods: In the present experimental study 3ml of peripheral blood samples were collected from 30 patients and 30 healthy subjects. The distribution of activation markers was evaluated by Immunophenotyping with anti-CD4, CD8, CD25, and CD69 antibodies. was used and output data were analyzed using Flow Jo 10 and SPSS 16 software.
Findings: Evaluation of the activation markers located T cells of patients with showed a significant decline by 0.8% and 2% in the expression of CD25 marker and 1.92% and 2.12% in the expression of CD69 marker on CD8+ CD4+ T cells, respectively (p<0.05).
Conclusion: The changes in the phenotype properties of T cells and the decreased expression of activation markers in high-level cholesterol conditions might weaken the immune system in hyperlipidemia patients.
Volume 23, Issue 2 (Spring 2020)
Abstract
Aims: Smokers are exposed to significant quantities of oxidative factors. The exercise has been shown to increase activation of antioxidant enzymes and reduce the production of free radicals in the body. Therefore, the present study was investigated the effect of 12 weeks of combined training on oxidative stress and antioxidants capacity in smoker's football players.
Materials & Methods: 22 smoker's football players with normal weight and the average age of 23.9±1.9 years were randomly divided into two experimental and control groups. The experimental group submitted to combine training including aerobic and resistance exercise (3 sessions per week) for 12 weeks. Antioxidant indicators (catalase and superoxide dismutase) and lipid peroxidation indicator (malondialdehyde) were measured 48 hours before and after protocol at least 8 hours of fasting. Dependent t-test was used to investigate the differences within the group data, and independent t-test was applied to investigate intergroup differences. The significance level was p≤0.05.
Findings: 12 weeks of combined training (aerobic and resistance) was caused respectively significant increase and decrease amounts of enzymes CAT and SOD as antioxidant indicators and MDA as lipid peroxidation indicators in smoker's football players (p≤0.05).
Conclusion: Combined exercise training (aerobic and resistance) likely by increase antioxidant capacity and decrease lipid peroxidation indicators eliminates the oxidative stress in smoker's football players.
Volume 25, Issue 1 (Winter 2022)
Abstract
Introduction: endurance and resistance exercise and the consumption of hawthorn alone and in combination have an effect on Alzheimer's disease.This study was conducted with the aim of the effect of hawthorn consumption and exercise on the inflammatory indices of Alzheimer's rats by trimethyltin chloride (TMT).
Materials and methods: rats were randomly divided into 9 healthy control and Alzheimer's groups with interventions (control, endurance training, resistance training, combined training, hawthorn, endurance training + hawthorn, resistance training + hawthorn, combined training + hawthorn). Then Alzheimer's disease developed. performed resistance , combined ,endurance exercises every week (12 weeks). Finally, blood was taken from the inferior vena and the inflammatory variables CRP, IL-6 ,TNF-α were measured by ELISA method. The Shapiro-Wilk test was used to check the normal distribution of the data, and the one-way analysis of variance (ANOVA) was used to check the mean difference between the groups (Tukey's test). P <0.05 were considered statistically significant.
Results: results showed that the induction of Alzheimer's disease induced by TMT caused a significant increase in the levels of TNF α, IL 6, CRP in the Alzheimer's control group compared to the healthy control. And 12 weeks of combined training with and without hawthorn had a significant decrease in the level of these variables compared to Alzheimer's control.
Conclusion: As a result, endurance and resistance sports along with the consumption of hawthorn lead to the reduction of some inflammatory factors in Alzheimer's rats.
key words: Alzheimer Disease, Hawthorn
TNF-α , CRP , IL-6 .
Volume 25, Issue 2 (Spring 2022)
Abstract
Introduction: Ferritin is an indicator of iron (Fe) storage in the body and plays the main role of cellular oxidation. It is hypothesized that Fe causes insulin resistance and then by reducing insulin secretion leads to type 2 diabetes. Considering the effects of exercise training in increasing insulin sensitivity, this study was designed the effect of various resistance (DR), endurance (DE), and combined (DER) activities on serum ferritin and Fe levels in diabetic rats. Materials and methods: Type 2 diabetes was induced by intraperitoneal injection of Nicotinamide solution (120 mg/kg) and Streptozotocin (65 mg/kg). One week after the confirmation of diabetes, the training groups underwent DR, DE and DER exercises for 10 weeks. After completing the research protocol, blood sampling was done to measure serum ferritin and Fe levels. Results: Type 2 diabetes caused an adverse increase in blood glucose, insulin levels, increased HOMA-IR, Fe, serum ferritin and decreased HOMA-IS. Looking to improve glycemic indices after 10 weeks of DE, DR and DER training, we saw a decrease in serum Fe and ferritin levels, and DER training had a significant decrease in Fe compared to DR and DE training. Conclusion: This study shows that serum iron and ferritin levels in diabetes are significantly increased and increased ferritin may be one of the reasons for insulin resistance in diabetes. Given the importance of iron and ferritin levels in insulin resistance, combined exercise with moderate intensity and time by reducing these biomarkers can reduce glycemic indices in diabetes.
